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IonSep DEAE 52 cellulose (DE52)



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IonSep DEAE 52 Cellulose; DE52

Preswollen DEAE-Cellulose for weak anion exchange chromatography

Diethylaminoehtyl Cellulose, DEAE 52, DE52, CAS#: 9013-34-7

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IonSep DEAE 52 is a preswollen DEAE cellulose weak anion exchange resin (Diethylaminoethyl cellulose) for anion exchange chromatography of proteins and nucleic acids. Formulated  preswollen for convenience and to provide high binding capacity and resolution.

  • Appearance: White microgranular (non-porous)
  • Granule size: 25 - 60um
  • Exchange capacity (mmol/g, dry): 0.9 - 1.4
  • Water content %: 65 - 75
  • Max flow rate (ml/min.): 50
  • Column volume (ml/g): 6.5
  • Protein loading capacity (BSA, pH 8.5, mg/g, dry): 550-900


DEAE Cellulose - Anion exchangers (basic types):

This DEAE cellulose anion exchange resin can be applied in ion exchange chromatography for the separation of serum components, enzymes, peptides, polysaccharides, RNA-types, viruses, lipids and ribosomes have been separated. DEAE cellulose is suitable for purification of nucleic acids.

As seen in Genetic Engineering News, New Product, Preswollen Cellulose, August 2018 issue. 

Instructions for use of DEAE 52 and CM 52

Specifications for DEAE 52

By on04 May 2018 (IonSep DEAE 52 cellulose (DE52)) :

DEAE cellulose

We've used Biophoretics Ionsep DE 52 for a few years in our mAb work; it has consistently performed and so has their service.
D. Raines,

By on13 Jan. 2017 (IonSep DEAE 52 cellulose (DE52)) :


At first we tested a small batch and found it met our needs; it did. Then we scaled-up and it consistently performs for us; good alternative to the forever missing Whatman product. One more thing, availability was great.