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Diethyl pyrocarbonate (DEPC, Ethoxy formic anhydride, Pyrocarbonic acid diethyl ester), CAS 1609-47-8, SERVA

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Diethyl pyrocarbonate

research grade


(DEPC, Ethoxy formic anhydride, Pyrocarbonic acid diethyl ester)
C6H10O5Mr 162.14CAS 1609-47-8


Crosslinks proteins, reacts with histidine residues. RNase inhibitor.

Sterilization of instruments: 20-minute treatment with a dilution of 1 ml/l.

Removal of RNases from solutions (except those containing amines like Tris):

Add DEPC to final conc. of 0.1 %, stir overnight and autoclave.


Assay (GC)min. 96.0 %


WARNING:  Hazardous Goods


EINECS: 216-542-8WGK: 1HS: 29209085
Storage Temperature: +2 °C to +8 °C