Poly D-lysine hydroBromide

Poly D-lysine by Serva Electrophoresis

Product Description:

poly-D-lysine hydrobromide by Serva Electrophoresis has been purified by dialysis, sterile-filtered on 0.2um, lyophilized, and stored under Argon gas

Poly-D-lysine hydrobromide with a molecular weight greater than 30,000 Da is recommended for cell culture applications. The poly-D-lysine hydrobromide (MW=52,000 Da) is easier to use because it is less viscous in solution, however the poly-D-lysine hydrobromide with an higher molecular weight (MW=84,000 Da) has more attachement sites per polymer chain available to the cells. Both poly-D-lysine hydrobromide and poly-L-lysine hydrobromide can be used as a coating substrate, however certain cells digest poly-L-lysine hydrobromide. In this case, poly-D-lysine, as the attachment factor, is necessary to prevent cell disruption by excessive uptake of L-lysine.